Lipid nanoparticles engineered to target therapeutic RNA to the pancreas

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In the 1960s, France became the third country, after the US and Soviet Union, to independently place a satellite (Astérix) into orbit, and the only country to send an animal into space and – crucially, for Félicette the catstronaut – bring it back alive. A decade later, the Franco-British Concorde flicked passengers across the Atlantic in three and a half hours and the TGV began to propel them through the countryside first at 250km/h (155mph), and then 320km/h. Then, in the late 1980s, the French space agency designed a crewed spaceplane, Hermès, that corrected for the Nasa space shuttle’s vulnerability by being integrated into its launch vehicle rather than perched atop it.